“Insane in the Brain” is a hit single by hip hop group Cypress Hill. It was released in 1993 and in addition to hitting number 1 on the US rap chart, the song also was a surprise crossover hit, reaching #19 on the Billboard Hot 100 in 1993. It was highly successful in other countries. The song was released on the group’s Black Sunday album. The popular lyric “Insane in the membrane” is sometimes confused for the title.
According to B-Real, the song was actually a diss song aimed at Chubb Rock. The group felt Chubb had ridiculed their style on his 1992 album. DJ Muggs produced the song Jump Around by House of Pain, which was later used to produce this song, with a couple of changes here and there. A video for the track was filmed at San Francisco’s DNA Lounge. Remember That?